5 ESSENTIAL ELEMENTS FOR PALMITOYLETHANOLAMIDE

2005). These results were not stunning if we consider that PEA is actually a inadequately h2o‐soluble material, that may limit its oral absorption and bioavailability, but they may also suggest a brief‐lived motion of PEA, in arrangement with The reality that this compound is degraded by two different hydrolases, that is, NAAA and FAAH. Later,

2016a). This smaller sized improve was proportionate on the smaller sized peak of PEA stages detected in human volunteers compared with beagle puppies. This difference, consequently, may be because of the decrease whole quantity of PEA acutely administered to human volunteers (about ∼five vs. 30 mg·kg−one in dogs) and to the fact that this wa